Giving Tuesday 2025

Thanks to years of sustained advocacy, 2025 has been a landmark year for patient safety:

FDA updated the Xeloda (capecitabine) label with a black box warning (October 3, 2025) requiring DPYD genetic testing before treatment.
NCCN updated the Colon Cancer Guidelines (October 30, 2025) recommending pretreatment DPYD testing before capecitabine and fluorouracil.
Medicare’s decision to cover DPYD testing has set the pace nationally, with more commercial insurers adopting parallel coverage policies and recognizing the test as medically necessary.
More cancer centers and oncology societies are now moving toward routine implementation—directly increasing appropriate test utilization.

These changes did not happen on their own. They are the result of caregivers’ and advocates’ tireless efforts, persistent engagement with FDA and national guideline committees, and thousands of hours spent educating oncologists, insurers, policy teams, and hospital leadership.

Our nonprofit is entirely volunteer-run—but our impact is national.

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Why your donation matters:

Our advocacy serves to inform patients to demand testing before treatment, drives policy change, and creates the awareness clinicians need to order testing consistently.

Supporting AUDT is not only philanthropic; it is also an investment in the future of safe, evidence-based precision oncology.

Thank you for considering AUDT in your Giving Tuesday philanthropy. Donations can be made securely below.

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AUDT is a 501(c)(3) non-profit organization. All donations are tax deductible.

Donations will go towards supporting our efforts to improve the standard of care for cancer patients undergoing fluoropyrimidine chemotherapy (5-FU and/or Capecitabine), through advocacy, education, research and legislation.